Symbol
Name
ID

Jag1
jagged 1
MGI:1095416

Phenotype annotations related to liver/biliary system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hepatomegaly	Cirrhosis	Reduced number of intrahepatic bile ducts	Cholestasis	Cholestatic liver disease	Prolonged neonatal jaundice	Hepatocellular carcinoma
Disease(s) Associated with JAG1
Alagille syndrome

Mouse Phenotypes

liver/biliary system phenotype

abnormal liver vasculature morphology

liver hemorrhage

hepatic necrosis

abnormal bile duct morphology

abnormal bile duct development

abnormal cholangiocyte morphology

bile duct proliferation

dilated bile duct

abnormal liver morphology

abnormal bile secretion

cholestasis

abnormal liver physiology

jaundice

Availability

Mouse Genotype

Jag1^Ndr/Jag1^Ndr

Jag1^tm1Frad/Jag1^tm1Frad
Tg(Tagln-cre)1Her/0 (conditional)

Jag1^tm1Frad/Jag1^tm1Frad
Tg(Cdh5-cre)7Mlia/0 (conditional)

Jag1^tm1Grid/Jag1^tm1.1Loo
Tg(Alb1-cre)1Khk/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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